PSMA and FDG PET/CT Findings for Differential Diagnosis of Bone Metastasis in a Patient With Synchronous Small-cell Lung Cancer and Prostate Cancer.

Liu, Guanghui; Wang, Shu; Du, Bulin; Li, Yaming; Li, Xuena · Clin Nucl Med · 2025

case_report · Level V

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Abstract

A 66-year-old man presented with both small-cell lung cancer and prostate adenocarcinoma. Staging PET with 18 F-FDG PET/CT revealed increased uptake in the right pulmonary hilum, mediastinum, fifth cervical vertebra, and fifth lumbar vertebra. In contrast, subsequent 68 Ga-PSMA PET/CT revealed intense uptake only in the prostate and vertebrae, which demonstrated that the bone lesions had metastasized from prostate cancer.

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