The Management of Chronic Periprosthetic Joint Infection: No Longer Is It "One Size Fits All".

Hannon, Charles P; Della Valle, Craig J; Heckmann, Nathanael D; Meneghini, R Michael; Fillingham, Yale A · J Arthroplasty · 2025

review · Level V

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Abstract

Historically, the methods for treating chronic periprosthetic joint infection (PJI) have only encompassed a single option of two-stage exchange. However, our methods for treating chronic PJI have now expanded to include two-stage exchange, one-stage exchange, and the new kid on the block, the 1.5-stage exchange. The nuances of each procedure are different, from the patient selection to patient expectations. Understanding these differences is essential to successfully implement the expanding options for treating chronic PJI.

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