Unusual I-131 Accumulation in the Gallbladder and Intrahepatic Cholangiocarcinoma in a Patient With Papillary Thyroid Cancer.

Wang, Guoqiang; Han, Na; Wang, Congcong; Si, Zengmei; Wang, Xufu · Clin Nucl Med · 2025

case_report · Level V

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Abstract

It is rare to observe I-131 accumulation in the gallbladder and intrahepatic cholangiocarcinoma. We report a case of a 69-year-old woman with papillary thyroid cancer (PTC), who received radioactive I-131 therapy (RAIT) after total thyroidectomy and radical right neck dissection. Whole-body scan (WBS) after the RAIT showed that there were 2 abnormally intense foci in the right abdomen. SEPCT/CT showed that they were in the gallbladder and the caudate lobe of the liver. Biopsy of the caudate lobe revealed intrahepatic cholangiocarcinoma (ICC).

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