Intense 18 F-FAPI-04 Uptake in Bone Marrow Metastasis From Recurrent Postoperative Gastric Cancer Negative on 18 F-FDG PET/CT.

Chen, Haipeng; Liang, Jiucen; Liu, Zhidong; Zhang, Linqi; Zhang, Rusen · Clin Nucl Med · 2025

case_report · Level V

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Abstract

A 65-year-old woman presented with whole-body pain after a radical gastrectomy of gastric cancer. The patient was enrolled in a clinical trial of comparison 18 F-FDG and 18 F-FAPI-04 PET/CT in recurrent gastrointestinal tumor (No. IIT-2022-015#HYX#). Compared with non- 18 F-FDG avidity, 18 F-FAPI-04 PET/CT showed diffuse inhomogeneous intense tracer uptake of bone marrow. Subsequent bone marrow biopsy confirmed recurrent gastric cancer. This case revealed 18 F-FAPI-04 might be a promising radiopharmaceutical in the evaluation of bone marrow metastasis from recurrent gastric cancer.

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