In Motion: Experimental Evidence on Exercise and Breast Cancer in Women and Mice.

McTiernan, Anne · Clin Cancer Res · 2025

review · Level V

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Abstract

Strong evidence from observational studies shows that high levels of physical activity are associated with a reduced risk of breast cancer, with a dose-response effect. Human trials and animal models have identified mechanisms explaining these associations, which aid in designing prescriptions and guidelines for exercise in breast cancer prevention. See related article by Jones et al., p. 3377.

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