Diffuse-charge dynamics across a capacitive interface in a dc electric field.

Abstract

Cells and cellular organelles are encapsulated by nanometrically thin membranes whose main component is a lipid bilayer. In the presence of electric fields, the ion-impermeable lipid bilayer acts as a capacitor and supports a potential difference across the membrane. We analyze the charging dynamics of a planar membrane separating bulk solutions with different electrolyte concentrations upon the application of an applied uniform dc electric field. The membrane is modeled as a zero-thickness capacitive interface. The evolution of the electric potential and ion distributions in the bulk are solved for using the Poisson-Nernst-Planck equations. Asymptotic solutions are derived in the limit of thin Debye layers and weak fields (compared to the thermal electric potential).