The duality of disease: the Alzheimer's disease dilemma through the lens of nosos and asthenia.

Scarmeas, Nikolaos; Noriega de la Colina, Adrián · Brain · 2025

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Abstract

Scarmeas and Noriega De La Colina use the ancient Greek concepts of nosos (biological disease) and asthenia (functional decline) to frame the shift in Alzheimer’s disease diagnosis from clinical symptoms to biomarkers, calling for better public understanding of both biological presence and lived experience.