Controversies in Allergy: Does Using Epinephrine Always Mean Calling 911?

Wong, Lydia Su Yin; Anderson, Erik; Brooks, Joel P; Nowak-Wegrzyn, Anna · J Allergy Clin Immunol Pract · 2025

review · Level V

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Abstract

The current standard management of anaphylaxis recommends immediate activation of emergency medical services after epinephrine administration. Recently the American Academy of Allergy, Asthma & Immunology 2023 anaphylaxis practice parameter has provided a conditional recommendation that patients at low risk may observe initial response to epinephrine at home.

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