Prognostic Value of C-Reactive Protein in Adults With Tuberculous Meningitis: A Prospective Cohort Study.

Tugume, Lillian; Cresswell, Fiona V; Engen, Nicole W; Tukundane, Asmus; Kimuda, Sarah; Mugabi, Timothy; Namombwe, Suzan; Kagimu, Enock et al. · Clin Infect Dis · 2025

prospective_cohort · Level II

Where this comes from

Abstract

We enrolled 135 adults with tuberculous meningitis (TBM), including 83% with HIV. Participants with baseline C-reactive protein (CRP) ≥40 mg/L had 3 times higher odds of an 8-week modified Rankin scale ≥4 (adjusted odds ratio, 2.78; 95% CI: 1.28-6.04; P = .010). CRP is a viable prognostic biomarker in TBM.

Medical subject headings