68 Ga-DOTATATE PET/CT-Guided Surgical Resection for Complete Remission of Multifocal Insulinomas in a Father and Son With MEN1 Syndrome.

Tatoğlu, Mehmet Tarik; Uslu, Hatice · Clin Nucl Med · 2025

case_report · Level V

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Abstract

A 49-year-old father and his 18-year-old son were diagnosed with multiple endocrine neoplasia syndrome type 1 (MEN-1). 68 Ga-DOTATATE PET/CT detected several insulinomas, and subsequent surgical intervention resulted in a complete cure. The father and son patients have both experienced episodes of hypoglycemia, in addition to having a parathyroid adenoma and a pituitary adenoma. Patients exhibit elevated levels of insulin, C-peptide, calcium, corrected calcium, parathyroid hormone (PTH), and prolactin.

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