Evaluation of Metastatic Insulinoma With Severe Hypoglycemia Using 68 Ga-Exendin-4 PET/CT.
case_report · Level V
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- Record sourced from PubMed, PMID 40590104.
- Also identified by DOI 10.1097/RLU.0000000000006008.
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Abstract
A 52-year-old man was pathologically diagnosed with a pancreatic neuroendocrine tumor (pNET) and synchronous liver metastasis through debulking surgery 2 years ago. Recently, the patient showed recurrent severe hypoglycemia after receiving multiple treatments. 68 Ga-Exendin-4 PET/CT imaging revealed diffuse uptake in the skeleton and other metastatic sites, which 68 Ga-DOTANOC PET/CT grossly underestimated. This case highlights the crucial role of 68 Ga-Exendin-4 in the comprehensive and accurate evaluation of metastatic insulinomas.
Medical subject headings
- Insulinoma
- Hypoglycemia
- Positron Emission Tomography Computed Tomography
- Pancreatic Neoplasms