Beware of the Red Herring: Angiomatoid Fibrous Histiocytoma on 18 F-FDG PET/MRI.

Alkhulaifat, Dana; Liu, Amanda; States, Lisa J · Clin Nucl Med · 2025

case_report · Level V

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Abstract

Angiomatoid fibrous histiocytoma (AFH) is a rare soft-tissue tumor of intermediate malignant potential with a generally favorable prognosis. It predominantly occurs in adolescents and young adults with predilection for the extremities. Here, we present a case of AFH in an 8-year-old girl who presented with nonspecific symptoms of fatigue, weight loss, night sweats, and intermittent bilateral leg pain, more pronounced on the right side.

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