Managing noninsulin glucose-lowering medications before surgery: A comparison of clinical practice guidelines.

Morey-Vargas, Oscar L; Gossmann, Mona; Ketz, Jeffrey M; Abdelmalak, Basem B · Cleve Clin J Med · 2025

review · Level V

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Abstract

Preoperative management of noninsulin glucose-lowering medications can be challenging as clinicians navigate adjustment amid decreased oral intake while maintaining euglycemia and avoiding hyper- or hypoglycemia. The authors review current published guidelines, along with the local protocol currently in place at Cleveland Clinic, to help clinicians determine which noninsulin glucose-lowering drugs may need to be held preoperatively and for how long.

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