Differentiating treatment episodes from gaps in eyes with diabetic macular oedema.
Where this comes from
- Record sourced from PubMed, PMID 40592585.
- Also identified by DOI 10.1136/bjo-2025-327238 and PMC identifier 12573354.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
The treatment of diabetic macular oedema (DMO) likely involves a series of treatment episodes separated by gaps during which no vascular endothelial growth factor inhibitor injections are delivered. Our aim is to differentiate the episodes and gaps with the isolation forests algorithm using the Fight Retinal Blindness! registry. We analysed 11 786 injection intervals (12 803 injections) and found that the period between adjacent injections≥38 weeks (95% CI 34 to 43 weeks) apart could be regarded as a treatment gap. The results will allow treatment episodes to be isolated so that the treatment patterns of DMO can be characterised more accurately.
Medical subject headings
- Macular Edema
- Diabetic Retinopathy
- Angiogenesis Inhibitors
- Ranibizumab