How To Interpret Subgroup Analyses from Prospective Randomized Clinical Trials: What Clinicians Need To Know.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 40592689.
- Also identified by DOI 10.1016/j.eururo.2025.06.015.
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Abstract
Subgroup analyses must be approached with caution. Only prespecified, well-powered analyses with formal interaction testing and validation can support strong claims; exploratory findings require confirmation. Integration of statistical rigor with clinical insight maximizes the value of subgroup analyses.
Medical subject headings
- Randomized Controlled Trials as Topic
- Research Design