Muscle needs NAD, but how much?
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 40602366.
- Also identified by DOI 10.1016/j.cmet.2025.06.001.
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Abstract
Supplements that increase nicotinamide adenine dinucleotide (NAD) have become increasingly popular, and much of the attention has focused on potential benefits to skeletal muscle. In this issue of Cell Metabolism, Chubanava et al.<sup>1</sup> use an inducible model to lower NAD concentration in the muscles of adult mice, revealing a surprising lack of functional consequences.
Medical subject headings
- NAD
- Muscle, Skeletal