Beyond transplantation: Gene-edited pig liver supports function in a human host.

Hara, Hidetaka; Wang, Yi · Cell Stem Cell · 2025

case_report · Level V

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Abstract

A recent study in Nature demonstrates that a gene-edited pig liver can function in a brain-dead human for short-term support. This highlights the potential of xenogeneic liver transplantation as bridge therapy and opens new directions in regenerative medicine and cross-species organ engineering.

Medical subject headings