Left Ventricular Assist Device, Implantable Cardioverter Defibrillator, and Radiation Therapy: A Technical Report, Review of Literature, and Recommendations.

Bennassi, Alexander; Truong, Tony; To, Nhu Hanh; Boukhobza, Chahrazed; Ksouri, Wassim; Belaïdi, Lahcène; Bellefkih, Fatimah-Zara; Rida, Hanan et al. · Pract Radiat Oncol · 2026

review · Level V

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Abstract

Recent advancements in cardiology have significantly improved survival and quality of life for patients with severe heart conditions, including those requiring implantable cardioverter defibrillators (ICDs) and left ventricular assist devices (LVADs). Radiation therapy (RT) using either conventional or advanced techniques, such as stereotactic body RT, remains a cornerstone treatment for cancer. However, managing patients with both ICDs and LVADs during RT presents unique challenges caused by potential device malfunctions and interactions with radiation. In this report, we present a case of a patient with both a triple-chamber ICD and an electronically equipped LVAD undergoing RT. The study explores the dosimetric considerations, device interactions, and adapted simulations required to minimize risks. This work aimed to bridge the knowledge gap and provide recommendations for the safe and effective integration of RT delivery in patients with advanced cardiac devices.

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