Superiority of 18 F-FAPI PET/CT to 18 F-FDG PET/CT in the Evaluation of Synchronous Renal and Uterine PEComa.

Yan, Sha; Li, Shuyi; Zhong, Yuehong; Zhang, Rusen; Zhang, Linqi · Clin Nucl Med · 2026

case_report · Level V

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Abstract

A 24-year-old woman presented with abdominal distension for 1 week. Abdominal contrast-enhanced CT showed 2 abnormal enhanced lesions in uterine fundus and in the lower pole of the right kidney, suggesting a probability of malignancies. As part of a clinical trial, the patient underwent both 18 F-FAPI and 18 F-FDG PET/CT to assess the malignancy of the lesions. Compared with 18 F-FDG PET/CT, 18 F-FAPI PET/CT demonstrated more intense and extensive tracer uptake in these lesions. Finally, pathologic analysis confirmed perivascular epithelioid cell tumors.

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