Lipidomic Signatures of Insulin Resistance Identified From Hyperinsulinemic-Euglycemic Clamp Studies in Asian Men.
cross_sectional · Level IV
Where this comes from
- Record sourced from PubMed, PMID 40644319.
- Also identified by DOI 10.2337/db25-0010 and PMC identifier 12365417.
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Abstract
The underlying molecular pathogenesis of the Asian phenotype of insulin resistance remains to be understood. We carried out metabolic phenotyping of study participants without diabetes according to insulin sensitivity indices derived from hyperinsulinemic-euglycemic clamp procedures. We identified lipidomic signatures of insulin resistance and metabolic plasticity. These lipidomic signatures have the potential to help in risk stratification of insulin resistance and metabolic dysfunction for early intervention.
Medical subject headings
- Insulin Resistance
- Lipidomics