Mimicking Lymphoma: A Rare Case of Extramedullary Plasmacytoma in Lymph Nodes on 18 F-FDG PET/CT.

Chen, Shaoming; Xue, Qianqian; Lin, Zefang; Liu, Qun; Miao, Weibing · Clin Nucl Med · 2025

case_report · Level V

Where this comes from

Abstract

Extramedullary plasmacytoma involving multiple lymph nodes is extremely rare. We report FDG PET/CT findings of multiple extramedullary plasmacytomas involving lymph nodes in a 71-year-old man. A chest CT scan revealed multiple enlarged lymph nodes in the right supraclavicular region, hilum, and mediastinum, merging into several soft tissue masses suggestive of lymphoma. On FDG PET/CT, these masses demonstrated intense 18 F-FDG uptake, mimicking aggressive lymphoma. No other abnormal tracer uptake was identified. Biopsy of the right supraclavicular lymph node confirmed the diagnosis of plasmacytoma.

Medical subject headings