The generative era of medical AI.

Fahrner, L John; Chen, Emma; Topol, Eric; Rajpurkar, Pranav · Cell · 2025

review · Level V

Where this comes from

Abstract

Rapid advancements in artificial intelligence (AI), particularly large language models (LLMs) and multimodal AI, are transforming medicine through enhancements in diagnostics, patient interaction, and medical forecasting. LLMs enable conversational interfaces, simplify medical reports, and assist clinicians with decision making. Multimodal AI integrates diverse data like images and genetic data for superior performance in pathology and medical screening. AI-driven tools promise proactive, personalized healthcare through continuous monitoring and multiscale forecasting. However, challenges like bias, privacy, regulatory hurdles, and integration into healthcare systems must be addressed for widespread clinical adoption.

Medical subject headings