A perspective for adapting generalist AI to specialized medical AI applications and their challenges.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 40646157.
- Also identified by DOI 10.1038/s41746-025-01789-7 and PMC identifier 12254199.
- Licence recorded as CC BY-NC-ND.
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Abstract
We introduce a framework to adapt large language models for medicine: (1) Modeling: breaking down medical workflows into manageable steps; (2) Optimization: optimizing model performance via advanced adaptations; and (3) System engineering: developing agent or chain systems. Furthermore, we describe varied use cases, such as clinical trial design, clinical decision support, and medical imaging analysis. Finally, we discuss challenges and considerations for building medical AI with LLMs.