Early Postnatal Polymerase Chain Reaction Testing in the Identification of Perinatal Transmission of Hepatitis C Virus.

Prasad, Mona; Sandoval, Grecio J; Saade, George R; Hughes, Brenna L; Clifton, Rebecca G; Reddy, Uma M; Bartholomew, Anna; Salazar, Ashley et al. · Clin Infect Dis · 2026

case_series · Level IV

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Abstract

In this study, a single hepatitis C virus (HCV) RNA at 2-6 months was sensitive and specific (86.7% and 95% confidence interval [CI], 62.1%-96.3% and 100% and 95% CI, 98.8%-100%, respectively) in identifying perinatal transmission of HCV. No cases of perinatal infection requiring treatment were missed.

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