Biopsychosocial phenotyping of patients with chronic low back pain using the pain and disability drivers management model: A retrospective cohort study.

Le Cam, Stéphane; Artico, Romain; Yameogo, Wendyam Nadège; Tousignant-Laflamme, Yannick; Fautrel, Bruno; Bailly, Florian · J Back Musculoskelet Rehabil · 2025

retrospective_cohort · Level III

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Abstract

BackgroundChronic low back pain (CLBP) is a major burden. The Pain and Disability Drivers Management (PDDM) model is a framework developed to analyse factors contributing to disability and pain in CLBP patients.ObjectiveThe primary objective was to explore the prognostic value of the PDDM model using real-life data. The secondary objective was to explore its analytical value.MethodsA monocentric retrospective cohort study included CLBP patients who underwent a multidisciplinary rehabilitation program between January 2014 and December 2020. Regression analyses were performed using the five domains of the PDDM as explanatory variables. To assess its prognostic value, the main outcome was the change in disability over the course of the program. Secondary outcomes were change in pain and return to work. To assess its analytical value, the outcome was baseline disability.ResultsCognitive-emotional domain of the PDDM predicted change in disability. Nociceptive, Nervous System Dysfunction and Cognitive-Emotional domains of the PDDM were associated with baseline disability.ConclusionsThe PDDM model showed limited prognostic value in our context but provided valuable insights into the bio-psycho-social dimensions contributing to disability in CLBP patients.

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