FedGAN: Federated diabetic retinopathy image generation.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 40705831.
- Also identified by DOI 10.1371/journal.pone.0326579 and PMC identifier 12289037.
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Abstract
Deep learning models for diagnostic applications require large amounts of sensitive patient data, raising privacy concerns under centralized training paradigms. We propose FedGAN, a federated learning framework for synthetic medical image generation that combines Generative Adversarial Networks (GANs) with cross-silo federated learning. Our approach pretrains a DCGAN on abdominal CT scans and fine-tunes it collaboratively across clinical silos using diabetic retinopathy datasets. By federating the GAN's discriminator and generator via the Federated Averaging (FedAvg) algorithm, FedGAN generates high-quality synthetic retinal images while complying with HIPAA and GDPR. Experiments demonstrate that FedGAN achieves a realism score of 0.43 (measured by a centralized discriminator). This work bridges data scarcity and privacy challenges in medical AI, enabling secure collaboration across institutions.
Medical subject headings
- Diabetic Retinopathy
- Diabetic Retinopathy/diagnostic imaging
- Humans
- Algorithms
- Deep Learning
- Tomography, X-Ray Computed
- Image Processing, Computer-Assisted
- Image Processing, Computer-Assisted/methods