Severity of Bronchopulmonary Dysplasia in Infants Born Extremely Preterm and Randomized to Early Human Milk Fortification with a Donor Milk-Derived Fortifier for 2 Weeks.

Tucker, Marley J; Jeffcoat, Seabrook H; Argent, Tori; Travers, Colm P; Salas, Ariel A · J Pediatr · 2025

rct · Level II

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Abstract

In this secondary analysis of a masked clinical trial involving 150 infants born extremely preterm randomized to receive fortified milk starting on either postnatal day 3 (early group) or day 14 (delayed group), we found a significant difference in the distribution of bronchopulmonary dysplasia severity between the 2 groups (P = .039) with milder forms of bronchopulmonary dysplasia in the early group.

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