Assessing microbiome engraftment extent following fecal microbiota transplant with q2-fmt.

Herman, Chloe; Bolyen, Evan; Simard, Anthony; Gehret, Liz; Caporaso, J Gregory · PLoS Comput Biol · 2025

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Abstract

We present q2-fmt, a QIIME 2 plugin that provides diverse methods for assessing the extent of microbiome engraftment following fecal microbiota transplant. The methods implemented here were informed by a recent literature review on approaches for assessing FMT engraftment, and cover aspects of engraftment including Community Coalescence, Indicator Features, and Resilience. q2-fmt is free for all use, and detailed documentation illustrating worked examples on a real-world data set are provided in the project's documentation.

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