Role and Use of Race in Artificial Intelligence and Machine Learning Models Related to Health.

Were, Martin C; Li, Ang; Malin, Bradley A; Yin, Zhijun; Coco, Joseph R; Collins, Benjamin X; Clayton, Ellen Wright; Novak, Laurie L et al. · J Med Internet Res · 2025

review · Level V

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Abstract

The role and use of race within health-related artificial intelligence (AI) and machine learning (ML) models have sparked increasing attention and controversy. Despite the complexity and breadth of related issues, a robust and holistic framework to guide stakeholders in their examination and resolution remains lacking. This perspective provides a broad-based, systematic, and crosscutting landscape analysis of race-related challenges, structured around the AI and ML life cycle and framed through "points to consider" to support inquiry and decision-making.

Medical subject headings