All-Cause Mortality in People With Four-Class Drug-Resistant HIV: A Matched Cohort Analysis With Data From the PRESTIGIO Registry.

Giacomelli, Andrea; Capra, Nicolò; Lolatto, Riccardo; Gagliardini, Roberta; Clemente, Tommaso; Calza, Leonardo; Torti, Carlo; Lagi, Filippo et al. · Clin Infect Dis · 2025

retrospective_cohort · Level III

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Abstract

People with human immunodeficiency virus (HIV) (PWH) with 4-drug class resistance (4DR) had a higher risk of death than non-4DR PWH, primarily due to lower CD4 cell counts. The priority for this vulnerable population is achieving virological control to enable immune recovery.

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