Medical Cannabis as the Source of Cryptococcus neoformans Infection.

Hughes Kramer, Kailey; Marino, Christopher C; Driscoll, Eileen; Cheng, Shaoji; Phillips, Kaitlin; Volpe, Peter J; Clancy, Cornelius J; Nguyen, M Hong · Clin Infect Dis · 2025

case_report · Level V

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Abstract

Whole-genome sequencing demonstrated that Cryptococcus neoformans serotype A from cerebrospinal fluid and larynx of a patient receiving therapy for refractory multiple myeloma and from the patient's medical cannabis were indistinguishable. This is the first study to definitively link an infection to a pathogen in medical cannabis used by a patient.

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