Calories to satiation-A new predictor of anti-obesity therapy outcome?

Edwin Thanarajah, Sharmili; Arjune, Sita; Hanssen, Ruth · Cell Metab · 2025

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Abstract

Despite advances in elucidating obesity pathophysiology, predicting individual responses to weight loss interventions remains challenging. Cifuentes et al.<sup>1</sup> developed a predictive model integrating genetic risk scores and anthropometric parameters to estimate caloric intake to satiation, demonstrating potential in forecasting weight loss trajectories with phentermine-topiramate and liraglutide therapies.

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