Low Level of Ambient Carbon Monoxide Exposure and Blood Pressure: A Longitudinal Panel Study at the Hourly Level.

Yang, Liyan; Yuan, Zhi; Miao, Lin; Lin, Zhijing · J Occup Environ Med · 2025

cross_sectional · Level IV

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Abstract

We aimed to study the acute link between ambient carbon monoxide (CO) and blood pressure (BP). A panel study of 40 college students with 4 repeated health examinations measured systolic blood pressure (SBP), diastolic blood pressure (DBP), and mean arterial pressure (MAP). CO data came from a nearby monitoring station. Liner mixed-effect models with lagged periods were used. Elevated SBP (lag 0-72 hours to 0-4 days), DBP (lag 0-12 hours to 0-4 days), and MAP (lag 0-12 hours to 0-4 days) were linked to CO. Single-lag effects appeared at 7 to 12 hours to 25 to 48 hours. Females (i.e., 5.06 mm Hg SBP) and abnormal body mass index individuals (i.e., 4.14 mm Hg SBP) showed higher BP. We observed acute subclinical adverse cardiovascular effects of CO exposure, evidenced by induced elevation in BP.

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