Vascular organoids get a speed boost for regenerative repair.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 40780186.
- Also identified by DOI 10.1016/j.stem.2025.07.002.
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Abstract
Gong et al. present a transcription factor-guided 3D differentiation that rapidly generates vascular organoids from human iPSCs, enhancing engraftment and revascularization of ischemic limbs and transplanted pancreatic islets in mouse models.<sup>1</sup> This approach establishes a scalable platform for generating functional vasculature, supporting both disease modeling and regenerative therapy development.
Medical subject headings
- Organoids
- Regeneration
- Regenerative Medicine