Interagency Collaboration for Patient-Centered Antibacterial Drug Development.

Howard-Anderson, Jessica; Doernberg, Sarah B; Dixon, Dennis; Gopinath, Ramya; Rubin, Daniel; Kinamon, Tori; Kim, Peter; Collyar, Deborah et al. · Clin Infect Dis · 2025

expert_opinion · Level V

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Abstract

This manuscript presents key advances of the Antibacterial Resistance Leadership Group (ARLG) Innovations Task Force, a collaboration focused on improving endpoints for registrational trials of antibacterial drugs, including health-related quality-of-life measures, for common acute infections. This group includes members from the United States Food and Drug Administration, National Institutes of Health, academia, industry, and patient representatives to amplify patient voices and ensure that the endpoints are meaningful to how patients feel, function, and survive.

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