Comparative Utility of 68 Ga-FAPI PET/CT and 18 F-FDG PET/CT in Assessing Treatment Response in a Case of Metastatic Anal Melanoma With Brain Involvement.
case_report · Level V
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- Record sourced from PubMed, PMID 40795804.
- Also identified by DOI 10.1097/RLU.0000000000005985.
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Abstract
A 59-year-old man with metastatic melanoma and brain metastases underwent brain radiotherapy. Following treatment, he developed neurological symptoms, prompting further evaluation. To assess the treatment response and possibility of Lutetium-177-FAPI therapy, both 18 F-FDG PET/CT and 68 Ga-FAPI-46 PET/CT scans were performed. The 18 F-FDG PET/CT was inconclusive due to posttreatment changes, making it challenging to distinguish between tumor progression and therapy-related alterations. In contrast, the 68 Ga-FAPI-46 PET/CT revealed multiple areas of increased FAPI uptake, indicative of viable residual lesions and consistent with MRI findings.
Medical subject headings
- Positron Emission Tomography Computed Tomography
- Melanoma
- Fluorodeoxyglucose F18
- Brain Neoplasms
- Anus Neoplasms