Implementation of Doxy-PEP in a Diverse Sexual Health Program in Northern Manhattan: The Doxy-Care Study.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 40811776.
- Also identified by DOI 10.2105/AJPH.2025.308209 and PMC identifier 12424490.
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Abstract
This prospective cohort study evaluated the real-world effectiveness of doxycycline postexposure prophylaxis use in reducing bacterial sexually transmitted infections (STIs) within a diverse urban sexual health program. Propensity-matched analyses showed significant STI reductions, particularly in rectal <i>Chlamydia trachomatis</i> infections, among early adopters. Uptake was disproportionately higher in non-Hispanic White individuals and those more engaged in care. Findings emphasize the need for targeted outreach to improve care engagement and equitable access to this STI prevention strategy. (<i>Am J Public Health</i>. 2025;115(10):1584-1588. https://doi.org/10.2105/AJPH.2025.308209).
Medical subject headings
- Sexual Health
- Doxycycline
- Sexually Transmitted Diseases
- Anti-Bacterial Agents
- Pre-Exposure Prophylaxis