A Wireless and Reusable OLED Patch for Accelerated In Vivo Skin Wound Healing.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 40830078.
- Also identified by DOI 10.1021/acs.nanolett.5c02534.
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Abstract
A fully wireless and reusable red organic light-emitting diode (OLED) patch was developed as a noninvasive platform for skin wound phototherapy. The device integrates a USB-C rechargeable battery, a flexible printed circuit board, and a red OLED emitter into a soft, skin-conformal form factor. The OLED delivers uniform 645 nm light with minimal heat (∼21 °C) and stable radiance (21.3 W/sr/m<sup>2</sup>) over 500 h. In a murine full-thickness wound model, a single session of irradiation (2.6-3.9 J/cm<sup>2</sup>) significantly accelerated wound closure, increased collagen synthesis, and enhanced epidermal differentiation. Immunohistochemical analysis further confirmed reduced inflammation and improved tissue maturation. Unlike previous OLED-based systems that required rigid encapsulation or wired power, this patch enables convenient, home-based light therapy without clinical supervision. The platform demonstrates strong potential as an electroceutical device for personalized dermatologic care and regenerative medicine.
Medical subject headings
- Wound Healing
- Skin
- Phototherapy
- Wireless Technology