A Photo-Patternable Solid-State Electrolyte for High-Performance, Miniaturized, and Implantable Organic Electrochemical Transistor-Based Circuits.

Xiong, Miao; Yang, Chi-Yuan; Ji, Junpeng; Caravaca, April S; Guo, Qi; Li, Qifan; Donahue, Mary J; Gao, Dace et al. · Adv Mater · 2025

basic_science · Level V

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Abstract

Organic electrochemical transistors (OECTs) are crucial for next-generation (bio-)electronic devices but are often constrained by the use of aqueous electrolytes, which introduce crosstalk, hinder miniaturization, and limit circuit integration. Here, a photo-patternable solid-state electrolyte based on 𝜄-carrageenan (𝜄-CGN) and poly(ethylene glycol) diacrylate (PEGDA) is presented, enabling high-performance OECTs and complementary circuits. The 𝜄-CGN electrolyte exhibits high ionic conductivity (>10 mS cm<sup>-1</sup>), comparable to a 0.1 m NaCl aqueous electrolyte, while supporting precise patterning down to 15 µm, fast transient response times, minimal hysteresis, and excellent stability in both p- and n-type OECTs. Compact solid-state NAND/NOR gates (500 × 800 µm<sup>2</sup>), 4-input NAND gates (1600 × 800 µm<sup>2</sup>, 8 OECTs), and half-adders (2 × 1 mm<sup>2</sup>, 18 OECTs) are demonstrated, all exhibiting correct logic functions and low-voltage operation. To highlight its potential for implantable bioelectronics, solid-state spiking circuits, monolithically integrated with flexible cuff electrodes, are developed for vagus nerve stimulation in mice. These findings establish 𝜄-CGN-based solid-state electrolytes as a promising platform for scalable, implantable circuits, paving the way for next-generation bioelectronic devices.

Medical subject headings