Established dietary interventions and time-restricted eating for cardiovascular disease prevention.

Abstract

Obesity and its associated metabolic disturbances, including insulin resistance, inflammation, hypertension, dyslipidemia, and plaque progression, are key drivers of cardiovascular risk. Established dietary strategies, such as the Mediterranean diet, Dietary Approaches to Stop Hypertension (DASH), and calorie restriction (CR), play a crucial role in preventing and slowing the progression of cardiovascular diseases (CVDs). Time-restricted eating (TRE) is a form of intermittent fasting where food intake is limited to 6-10 h daily, typically during daytime hours, and is showing potential to improve cardiovascular health. This review examines the evidence for and mechanisms underlying established dietary strategies and TRE in improving cardiovascular outcomes, and it explores whether incorporating established dietary interventions alongside TRE could provide synergistic cardiovascular benefits.