Evaluating the Effectiveness of Transforaminal Epidural Steroid Injections for Lumbar Radiculopathy Due to a Herniated Nucleus Pulpous Utilizing PROMIS as an Outcome Measure.

Stephens, Andrew R; Shinaman, Gregory J; Jacques, Chelsie L; El-Hassan, Ramzi; Patel, Rajeev K · Am J Phys Med Rehabil · 2026

retrospective_cohort · Level III

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Abstract

The purpose of this study was to evaluate the effect of transforaminal epidural steroid injection (TFESI) for patients with lumbosacral radiculopathy secondary to a lumbosacral herniated nucleus pulposus. A retrospective review of adult patients who received a fluoroscopically guided transforaminal epidural steroid injections for a herniated nucleus pulposus was performed. Patient-Reported Outcome Measurement Information System domains of physical function, pain interference, and depression were collected at baseline and postprocedure short-term (1-3 mos after procedure) and long-term follow-up (6-12 mos after procedure). Patient-Reported Outcome Measurement Information System physical function at short- and long-term follow-up statistically improved by 1.9 ( P = 0.02) and 4.6 ( P = 0.01) points, respectively. Patient-Reported Outcome Measurement Information System-pain interference at short- and long-term follow-up statistically improved by 3.7 ( P < 0.001) and 5.9 ( P = 0.002) points, respectively. Depression scores improved by 2.7 ( P = 0.04) at short-term follow-up, but long-term follow-up scores did not significantly differ from baseline scores. Ninety-one (85%) of patients did not elect for spine surgical consultation. Our study demonstrated that lumbosacral transforaminal epidural steroid injection was associated with a long-term improvement in function and pain for patients with lumbosacral radiculopathy due to a herniated nucleus pulposus as measured by Patient-Reported Outcome Measurement Information System-physical function and pain interference survey and obviated the need for spine surgery at long-term follow-up.

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