Awake surgery with direct electrical stimulation mapping and real-time cognitive monitoring for functionally guided tumor resection: how we do it.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 40913737.
- Also identified by DOI 10.1007/s00701-025-06656-8 and PMC identifier 12414027.
- Licence recorded as CC BY-NC-ND.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Awake surgery is the reference for diffuse low-grade glioma resection, allowing maximal tumor removal while preserving neurocognitive functions. It is also applicable to other brain tumors. However, key technical elements must be followed to ensure optimal conditions for intraoperative cognitive testing and reliable functional mapping. We describe the asleep-awake-asleep technique with real-time cognitive monitoring and provide practical guidance for safe and effective implementation. Success relies on rigorous intraoperative standards to optimize functional mapping. Beyond oncological outcomes, this surgical philosophy preserves quality of life by respecting individual brain organization, reflecting a shift toward personalized functional neurooncology.
Medical subject headings
- Brain Neoplasms
- Wakefulness
- Glioma
- Brain Mapping
- Neurosurgical Procedures
- Intraoperative Neurophysiological Monitoring
- Cognition
- Monitoring, Intraoperative