Behavioral Support by Ex-Smoking Peers Using Instant Messaging for Smoking Cessation: A Randomized Controlled Trial.

Guo, Ziqiu; Luk, Tzu Tsun; Weng, Xue; Wu, Yongda; Zhao, Shengzhi; Lai, Yuen Kwan; Cheung, Derek Yee Tak; Tong, Henry Sau Chai et al. · Chest · 2026

rct · Level II

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Abstract

Peer support could be beneficial for smoking cessation. Randomized controlled trial (RCT) evidence is lacking regarding mobile-based behavioral support offered by ex-smoking peers on smoking cessation in community people who smoke. Is mobile-based behavioral support provided by ex-smoking peers effective in promoting smoking cessation among community people who smoke? An RCT was conducted with people who smoked daily under the Hong Kong Quit-to-Win Contest 2021. All participants received brief smoking cessation advice at baseline. Each participant in the intervention group joined a 3-person chat group of instant messaging apps (eg, WhatsApp), which consisted of the person who smoked, a smoking cessation advisor, and a trained ex-smoking peer who had quit smoking for ≥ 1 year. Personalized behavioral support lasted 3 months through the chat group by ex-smoking peers, including experiences of quitting strategies, coping with withdrawal symptoms, use of smoking cessation services, and encouragement. The control group received 6 smoking cessation text messages and follow-up reminders. The primary outcome was biochemically validated abstinence at 6 months following intervention initiation. Analysis was by intention-to-treat using Poisson regression with robust variance. From June to September 2021, a total of 1,105 participants were randomly assigned to the intervention (n = 553) and control (n = 552) groups. At 6 months, compared with the control group, the intervention group showed a nonsignificant increase in biochemically validated smoking abstinence (8.9% vs 6.7%; risk ratio [RR], 1.32; 95% CI, 0.88-1.99) and more usage of smoking cessation services (14.5% vs 10.0%; RR, 1.45; 95% CI, 1.05-2.00). In the intervention group, participants who engaged in instant messaging support exhibited much more validated abstinence (22.2% vs 4.9%; RR, 4.52; 95% CI, 2.66-7.68). Behavioral support by ex-smoking peers via instant messaging was shown to be potentially effective and should be improved to increase smoking abstinence. ClinicalTrials.gov; No.: NCT04909320; URL: www. gov.

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