Impact of Hearing-Targeted and Universal Newborn Screening on the Observed Birth Prevalence of Congenital Cytomegalovirus Infection.

Kunzweiler, Colin; Stetson, Raymond C; Jacobson, Robert M; St Sauver, Jennifer L; Li, Yan; Jiang, Ruoxiang; Gadoth, Adva; Hendrix, Laura et al. · J Pediatr · 2026

retrospective_cohort · Level III

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Abstract

This retrospective study estimated the birth prevalence of congenital cytomegalovirus (cCMV) in southeastern Minnesota, US. The birth prevalence was about 3 times and about 18 times greater following implementation of hearing-targeted and universal newborn cCMV screening, respectively. Most infants born with cCMV will not be identified in the absence of systematic newborn screening programs.

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