How I do it: > 8 Carmustine wafer implantation during supra-marginal resection of a glioblastoma, IDH-wildtype.

Roux, Alexandre; Elia, Angela; Zanello, Marc; Pallud, Johan · Acta Neurochir (Wien) · 2025

case_report · Level V

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Abstract

The maximal safe resection of glioblastoma, IDH-wildtype often creates a large resection cavity that can accommodate more than eight Carmustine implants. We detail the implantation technique of 13 Carmustine wafers within the surgical bed after a right hippocampal formation-sparing anterior temporal lobectomy allowing for the supra-marginal resection of a glioblastoma IDH-wildtype in an adult patient. Carmustine wafer implantation is a safe and efficient technique following surgical resection of a glioblastoma, IDH-wildtype. Sequential technical steps are required to improve the safety and the efficacy of Carmustine wafer implantation. More than eight Carmustine wafers could be implanted in large surgical cavities with survival benefits for the patients.

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