Importance of 3D-TSE imaging for patients with brain metastasis treated with SRS alone.
retrospective_cohort · Level III
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- Record sourced from PubMed, PMID 41027511.
- Also identified by DOI 10.1016/j.radonc.2025.111172.
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Abstract
This study evaluates the clinical utility of 3D turbo spin echo (3D-TSE) imaging in stereotactic radiosurgery (SRS) planning for brain metastases, examining the value of adding 3D-TSE to MPRAGE. Dual-sequence MRI (MPRAGE + 3D-TSE) significantly prolonged time to distant intracranial failure (DIF) in whole brain radiotherapy (WBRT)-naïve patients (n = 308, 11.4 vs. 6.8 months, p = 0.03), but not in patients previously treated with WBRT and salvaged with SRS (n = 39, 6.5 vs. 5.6 months, p = 0.76). Additional lesion detection attributed to 3D-TSE imaging was greater in WBRT-naïve (19.6 %) than in post-WBRT patients (12.0 %) (p < 0.001). The dual-sequence imaging may improve time to distant failure in the modern era for most patients treated with primary stereotactic radiosurgery and should be integrated into the SRS workflow.
Medical subject headings
- Brain Neoplasms
- Radiosurgery
- Imaging, Three-Dimensional
- Magnetic Resonance Imaging