Quality assessment of artificial intelligence-generated versus human-written hospital summaries evaluating detail, usefulness, and continuity of care.

Challener, Douglas; Ayanian, Shant; Ryu, Alexander; O'Horo, John; Heaton, Heather · J Hosp Med · 2026

retrospective_cohort · Level III

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Abstract

Hospital discharge summaries are critical for ensuring continuity of care, but their quality often varies. Large language models (LLMs) have the potential to standardize and enhance the efficiency of this documentation process. To evaluate the quality of hospital discharge summaries created by an LLM-based hospital course drafting tool created by Epic Systems compared with human-written summaries. Retrospective study at a single tertiary-care institution in 2024. The cohort included 100 adult hospitalizations lasting >72 h across medical and surgical dismissing services. No interventions were performed. Summaries (LLM-generated vs. human-written) were independently reviewed using a standardized rubric covering nine domains (e.g., comprehensiveness, clarity, relevance). Scores were normalized and compared. Readability was assessed using Flesch Reading Ease. LLM-generated summaries outperformed human-written summaries across all criteria (p < .05), with the greatest difference observed in comprehensiveness (LLM median 0.62 vs. human -0.23). Human-written summaries from surgical services scored lower than those from medical services, but LLM performance was consistent across both. Human summaries had higher Flesch Reading Ease scores (33.11 vs. 26.2; p < .05), reflecting simpler language. LLM-generated summaries demonstrated superior quality, consistency, and clinical utility compared with human-written summaries, highlighting their potential to improve documentation efficiency and standardization.

Medical subject headings