Low-dose colchicine for management of coronary artery disease.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 41033847.
- Also identified by DOI 10.3949/ccjm.92a.25005.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Cardiovascular disease remains a leading cause of morbidity and mortality worldwide. Though inflammation plays an important role in atherogenesis, treatments directly targeting inflammatory pathways have had mixed results on improving clinical outcomes. Low-dose colchicine has been studied recently for the management of atherosclerotic cardiovascular disease. We explore the history of colchicine as an anti-inflammatory agent, review clinical trial data of colchicine for atherosclerotic cardiovascular disease, and discuss practical considerations for adding low-dose colchicine in this setting.
Medical subject headings
- Colchicine
- Coronary Artery Disease
- Anti-Inflammatory Agents