Roadmap for Representative Artificial Intelligence Models for Thyroid Cancer.

Ramchandani, Rashi; Guo, Eddie; Biglou, Sanaz G; Sabbah, Sami G; Mostowy, Michael; Mahiny, Donya; Hurtubise, Christian; Anicho-Okereke, Gift et al. · Laryngoscope · 2026

expert_opinion · Level V

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Abstract

Artificial intelligence (AI) models in thyroid cancer are often not generalizable due to biased or non-representative training and validation datasets. We propose a four-stage roadmap emphasizing representative data collection, inclusion of contextual variables, robust training/validation design, and post-deployment monitoring to improve fairness and clinical utility.

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