Raising the bar for human post-implantation embryo models.

Kong, Xiangyu; Theunissen, Thorold W · Cell Stem Cell · 2025

editorial · Level V

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Abstract

The generation of stem-cell-based embryo models has ushered in a new era for human embryology, but improving their reproducibility and lineage fidelity has remained a challenge. In this issue of Cell Stem Cell, Chen et al.<sup>1</sup> and Oura et al.<sup>2</sup> develop refined strategies to assemble human post-implantation embryo models with greater accuracy and efficiency, setting a new standard for the field.

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